International conference on Pharmaceutical Analytical Chemistry & Technology
September 10-11, 2018
“Exploring the Recent Trends & Advances in the Field of #Pharma and #Chemistry”
Allied Academies welcomes all the attendees, speakers, sponsor’s and other research expertise from all over the world to the “#International #Conference on #Pharmaceutical #Chemistry & #Technology” (#Pharmachemcongress 2018) which is going to be held during September 12-13, 2018 in #Dublin, #Ireland. We are very much honoured to invite you all to exchange and share your views and experience in #Pharmaceutical #Chemistry: “Exploring the Recent Trends & Advances in the Field of #Pharma and #Chemistry”. Allied Academies Organizes Pharma Chem Congress2018 along with 300+ Conferences across #USA, #Europe & #Asia every year with support from 1000 more scientific societies and Publishes 400+ Open access journals which contain over 30000 eminent personalities as editorial board members. We invite you to join us at the #Pharmachemcongress 2018, where you will be sure to have a meaningful experience with scholars from around the world. All members of the #Pharmachemcongress 2018 organizing committee look forward to meeting you in #Dublin, #Ireland.
Scope of #Pharmachemcongress 2018:
#Pharmachemcongress 2018 is a platform unites researches, scientists, professors from all over the world to create new contacts to share and spread innovative thoughts and recent advancement in the field of pharmaceutical chemistry & Technology. #Pharmachemcongress unites people who have an enthusiasm for various fields of #pharma and #Chemistry. Target audience will be workforce from both industrial and academic fields which incorporate; Professor, Researchers, Business monsters, Directors, Vice presidents, Co-executive, Managing Directors, Industry officers, Doctorates, Professors, Post Doctorate Fellows, Vendors of consumer products, #Pharmaceutical Scientists, Students from the related fields.
Recent Trends in Pharmaceutical Market:
Over the last decade, industry’s productivity has been decreasing with rising #R&D costs and time is taken to reach a market. #Medicinal chemistry is defined as a focused science that is developed to cover a wide-ranging of fields related to identification, synthesis and drug development for therapeutic applications. This science has evolved from medical chemists focusing on drug target or pathway in mind and league of elaborative #chemistry-driven processes to a modern generation of #high-throughput screening (HTS) libraries that are formed by combinatorial #chemistry based on limited structural distinctions across large #drug like scaffolds. This change was desired because of high attrition rate in pre-clinical and incubation drug development studies because of earlier methods. While the prime task of medicinal #chemists has not changed significantly over a period of time, the #computational tools and #chemicals and perspectives at their clearance or removal have advanced extensively.
The several tools of medicinal chemistry are in silico modeling, structure-based #drug design (SBDD), comparative molecular field analysis (CoMFA) or 3D QSAR method. In particular, the fragment-based drug design hopefully stands out because of substantial improvements in research and productivity. One of the main challenges of drug discovery is to design a robust drug that is both safe and effective in a wide range of the population. The several #drug designing types are structure-based #drug design, natural products-based #drug design, fragment-based #drug design, diversity concerned with synthesis and #chemogenomics.
Global Strategy of #Pharmaceutical market:
Due to modern technology an substitute approach to the large #combichem libraries (10,000 plus molecules) is available, these are minor focused arrays known as chemogenetic arrays that assist for confining of the particular #pharmacophore model for the specific family to target but considering ADME and drug-like properties. The compound arrays must be synthetically feasible and to minimize the attrition rate in preclinical testing, must also consist of definite properties regarding #adsorption, #distribution, #metabolism, #elimination, and toxicity (ADMET). During this process, the ADMET constraints traditional from information mining, #invitro and #invivo studies are often compiled into computational packages to enable chemists to predict the drug-likeliness of a compound. The current market trends observed with #medicinalchemistry operations are outsourced by most of the #pharmaceutical companies because this helps the companies to pace up the research process making it time and cost efficient. The outsourcing trend supposed from the North American and European pharmaceutical companies to the companies of developing companies like #India, #China, and Others from the #Asian continent. #Pharmaceuticals represented a US$300 bn-a-year market globally as of 2015, the #World Health Organization states. The global #pharmaceutical market is estimated to surpass US$400 bn by 2018, with the ten major #pharmaceutical companies collectively commanding about a third of the market. Companies in the #pharmaceutical industry are considered by their sizeable expenditure on #R&D and marketing initiatives in a bid to rake in more revenue. The development of #biopharmaceuticals represents a milestone for the industry and personalized therapies carry enormous promise in the near future. Although mature markets continue to account for over half of all global revenue of the #pharmaceutical industry, both large and niche #pharmaceutical companies are now rousing up to the lucrative potential that lies in growth markets. Costs associated with bringing innovative molecules to the commercial space are progressively rising. To add to this, new medicines launches have continued to chart a flat graph. This could, however, also be an enormous opportunity for #pharmaceutical companies in both matured and growth markets.